• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The invention relates to a device (1) for the temperature-controlled storage of stored goods (2), in particular of liquid substances such as blood samples, the device having receptacles (3) for the stored goods (2) and at least some of the receptacles (3) temperature control lines ( 5) through which tempering means for tempering the stored goods (2) flows. The object of the present invention is to provide a device of the type described which has improved efficiency. This object is achieved in that at least some of the receptacles (3) having temperature control lines (5) have at least one elastic element for fixing the stored goods (2).
    公开号:AT521831A1
    申请号:T50990/2018
    申请日:2018-11-13
    公开日:2020-05-15
    发明作者:Ing Dominik Radler Dipl；Filip Kitanoski Dr
    申请人:Productbloks Gmbh；
    IPC主号:
    专利说明:

    The invention relates to a device for the temperature-controlled storage of stored goods, in particular liquid substances such as blood samples, the device having receptacles for the stored goods and at least some of the receptacles having temperature control lines through which the temperature control means
    Temperature control of the stored goods flows.
    Devices of this type are mainly used to store sensitive products. Products such as living cells can be stored in blood or tissue samples at a defined temperature. The sample can be cooled on the one hand, for example to a few degrees Celsius or far below the freezing point of water. On the other hand, the product can also be kept at an elevated temperature. The latter is particularly interesting if a biological process is to be carried out or stimulated by the storage, for example an incubation.
    The stored goods are usually arranged in appropriate storage containers such as test tubes or bottles made of glass or plastic.
    CN 250156491 U1 describes a cooling device for blood samples, the storage vessels containing the blood samples being able to be inserted into receptacles. The recordings are supplied with temperature control agents through cooling lines and thus ensure rapid and energy-efficient cooling of the sample. However, it is disadvantageous that due to the air gap between the receptacle and the stored goods, the heat transport is low and the time until the optimum temperature is set depends on the size of the stored goods and thus the thickness of the pleasure gap. This increases heat or cold loss even with cooling or heating and thus increases energy consumption.
    The object of the present invention is thus a device of the described
    Provide type that has improved efficiency.
    According to the invention, this object is achieved in that at least some of the receptacles having temperature control lines have at least one elastic one
    Has element for determining the stored goods.
    The elastic element can reduce the air gap between the receptacle and the stored goods. This enables a better thermal connection, which requires an accelerated adjustment of the temperature of the stored goods to the storage temperature specified by the temperature control means. In particular, thermally labile products can be brought quickly to the specified temperature and their decay or deterioration in quality can be prevented. The elastic element should be so rigid that it fixes the stored goods sufficiently in the receptacle, but be so elastic that removal is possible if necessary.
    By defining it is meant that the position of the stored goods is stabilized to such an extent that it is not without sufficient external influence, such as through
    pulling out by a user leaves his position.
    Another advantage arises from this, since it allows storage goods of different sizes to be arranged in the receptacle. Even if the stored goods are smaller or have a geometry that does not correspond to the receptacle, it can
    unnecessary air gaps can be prevented.
    A water-glycol mixture is particularly advantageous as a temperature control agent when cooling the stored goods, since it is easy to handle and cool, inexpensive and non-toxic. Such a mixture is particularly advantageous at cooling temperatures of 0-10 ° C or when heating to above room temperature. Accordingly, a water-free temperature control agent such as oil or mineral oil can be useful at setpoint temperatures of 100 ° C or above. Another alternative would also be the use of directly evaporating substances as temperature control agents in order to achieve an even temperature distribution within the
    To reach storage goods.
    It can be provided that at least one spring element, as an elastic element, presses the temperature control line in the direction of a receptacle opening for receiving the stored goods of the receptacle. The spring element can, for example, be designed directly as a wire spring, which preferably presses a connecting surface of the temperature control line into a receiving opening of the receiving means. If a storage item is inserted into the receiving opening, the temperature control line is elastically pushed back by the storage item to the extent that it is
    finds enough space.
    The connection surface is preferably thermally well connected to the temperature control line, so that heat can also be dissipated via it. It can also be provided that the spring element is arranged in the receiving opening opposite the temperature control line and protrudes into the receiving opening. This pushes the stored goods onto the temperature control line. Alternatively, the spring element can also be arranged between the coolant line and the receiving opening. The spring element should preferably have good thermal conductivity
    be executed.
    The receiving opening is understood to mean a recess in the receptacle which is suitable for receiving at least part of the stored goods. As a rule, it is an opening with a hole for inserting the
    Storage goods, side walls and preferably also a floor.
    The spring element can also be designed as an elastic fabric like a sponge
    be.
    It is particularly advantageous if at least one temperature control line is at least partially elastic. This means that the temperature control line itself can act as an elastic element and can thus adapt to the outer contour of the stored goods. This enables a particularly good thermal transfer.
    The material for the temperature control line is particularly elastic
    Plastic, rubber or composite materials made of textiles and plastics.
    It can be advantageous if the temperature control line has at least one layer that is elastic. In particular, if the temperature control line is made of composite material at least in the elastic region, this can lead to a flexible, elastic but nevertheless tear-resistant and resistant embodiment variant.
    In order to achieve an improved heat transfer, the temperature control line can be designed to at least partially rest against a storage item arranged in the receptacle, preferably flat
    to lie on.
    If the receptacle has a receiving opening for receiving the stored goods and the temperature control line protrudes into the receiving opening in an unused position without stored goods in the receiving opening, the temperature control line can be displaced from the stored goods and out of the storage device when the stored goods are introduced into the opening Press the opening towards the outside. The temperature control line is thus automatically in contact with the stored goods.
    For better heat transfer, provision can be made for the temperature control line to be flat over at least in the area of a receiving opening for receiving the stored goods of the receiving device. With that a
    particularly large area facing the goods to be stored.
    In order to ensure a particularly effective cooling, it can be provided that a main flow of the temperature control means leads the temperature control line along the flat area. The main flow means the flow that carries most of the temperature control medium. This ensures that the heat transfer in the area works particularly well and completely.
    It can be provided that the temperature control line in the area of the receiving opening extends essentially over the entire height of the receiving opening
    extends.
    It is also particularly advantageous if the receiving opening is essentially cylindrical and at least one temperature control line forms at least a first part of the jacket. The temperature control line is preferably at least partially elastic. The temperature control line can thus form a pocket into which the stored goods can be inserted. The temperature control line can extend like a ring part around the receiving opening, so that it preferably assumes a Q shape. So that's one
    particularly good cooling achieved.
    In this regard, it is particularly advantageous if the receiving opening is essentially cylindrical and a first temperature control line has at least a first part of the jacket and a second temperature control line
    form a second part of the jacket of the receiving opening. The
    Tempering lines together form an elastic pocket into which the
    Storage goods can be inserted.
    The first temperature control line and the second temperature control line can be arranged essentially at the same height or can also be arranged offset to one another. The height is understood to mean the height of the receiving opening, ie the height that extends from the hole in the receiving opening into the receiving opening.
    In order to achieve a faster and more homogeneous adjustment of the temperature of the stored goods to the temperature of the temperature control medium, the first temperature control line and the second temperature control line can be in opposite directions
    Directions are flowed through by temperature control.
    In order to facilitate easier retrieval, in particular automatic retrieval, it can be provided that the elastic element defines a storage position of a storage item arranged in the receptacle.
    A very efficient cooling is achieved if the device has at least one receiving unit with several receptacles and the temperature control lines of the receptacles of the receiving unit are at least partially serially connected to one another. This enables effective cooling with little effort and simple construction. Alternatively, the
    Temperature control lines can also be supplied in parallel.
    In particular, if the time intervals between the classification of the stored goods in the receiving unit are relatively large, the temperature of the stored goods among themselves is not significantly influenced. The flow rate of the temperature control means is preferably selected such that the temperature of the temperature control means does not change significantly when a storage item is arranged with widely differing temperatures. If, for example, very hot stored goods are stored, the temperature of the temperature control fluid flowing past should still only increase by a few tenths of a degree if the stored goods are to reach a target temperature of, for example, 6 ° C. and the temperature control medium accordingly also has this temperature.
    It can be provided that several receiving units are provided, the temperature control lines of which are connected to one another in parallel. This means that several recording units can be arranged one above the other or next to one another,
    which is space-saving.
    In this context, serially means that the temperature control medium first flows through the temperature control line of a receptacle, in order to then flow through the temperature control line of another receptacle or multiple receptacles before it is adapted to a desired temperature by a heat sink or source. By parallel is meant that part of the temperature control medium flows through one temperature control medium line and another part through one or more further temperature control medium lines and these parts are then combined again. In other words, in the case of a serial connection of two temperature control lines, the output of the first temperature control lines is connected to the input of the second. In the case of a parallel connection, the inputs of the first and second temperature control lines and the outputs of the two temperature control lines are connected to one another accordingly. The recording units also allow any combination of parallel and
    serially connected recordings.
    For example, the evaporator of a compression refrigeration system or a thermoelectric system (e.g. Peltier element) can be used as a heat sink, and an electrical heating element or the condenser of a compression refrigeration system can be used as a heat source
    be used.
    The device can be designed so that the recording units also
    can be modularly assembled or unplugged.
    In order to achieve automatic or semi-automatic storage, the device can have at least one gripping arm for storing, retrieving or relocating the stored goods into or out of the receptacles. In this case, either the device or each receiving unit or both can have an insulated outer shell, with goods being able to be taken in and out at a defined storage and retrieval point. The gripping arm can, if necessary, arrange stored goods pushed into the receptacles or bring the stored goods out of the receptacles into the area of the storage and retrieval point in order to be removed
    to become.
    If at least some of the temperature control lines are connected to at least one heat sink or heat source, which preferably has at least one compressor, then it is easy to regulate the temperature
    can be achieved.
    In order to ensure adequate cooling, at least some of the temperature control lines can be supplied with temperature control from at least one heat sink. A heat sink can be assigned to each receiving unit
    be.
    It is particularly advantageous if a receiving unit is assigned to each heat sink or heat source. As a result, the heat sink or heat source can act as a unit together with the receiving unit and can be operated independently. In the following, the invention is not based on that shown in the figures
    restrictive design variants explained in more detail. Show it:
    Fig. 1a is a schematic side view of a first embodiment of a
    device according to the invention;
    1b is a schematic side view of a second embodiment of a
    device according to the invention;
    Fig. 2 shows a part of a recording unit with different
    Embodiments of rows of images in a top view;
    3 shows a schematic oblique view of a temperature control line;
    4a and 4b an embodiment of a receptacle in a section;
    1 a shows a device 1 in a first embodiment with a gripping arm 100 which can be moved in all directions 102 and three receiving units 10. The receiving units 10 are supplied in a parallel connection with temperature control means by a heat sink 202 comprising a compressor, that is to say a cooling system. For this purpose, each input line 200 of the receiving units 10 is connected to a supply line 201 of the heat sink 202 and each drain line 203 of the receiving units 10 is connected to the return line 204 of the heat sink
    202 connected. Each recording unit 10 has a total of ten recording rows 12
    on, each having a plurality of receptacles 3, into which stored goods 2 can be inserted through a hole 31 from the gripping arm 100. The receptacles 3 of each receptacle row 12 are arranged in a row, the receptacle rows 3 being arranged side by side. The receiving rows 3 are serially supplied by the supply line 201 and discharge the temperature control medium used via the drain line 203.
    Each receiving unit 10 also has a thermally insulating sheath 11. The receiving units 10 are thus essentially independent of one another and when a receiving unit 10 is disconnected or defective, there is no general failure of all the other receiving units 10. In addition, the temperature-controlled space is kept as small as possible Gripping arm 100 does not have to be arranged inside the temperature-controlled room. The stored goods 2 can protrude upward from the temperature-controlled areas, but this does no harm, since this area is very small and the product is pulled by gravity into the lower part of the stored goods 2, so that the product in the stored goods 2 is at a constant Temperature can be kept and the energy losses are low. Alternatively, thermally insulating closing mechanisms such as flaps can also be provided, which close the stored goods 2 upwards and from the
    Gripping arm 100 can be opened automatically.
    In the case of directional information as above or below, an intended arrangement of the device 1 is assumed, in which holes 31 of the receptacles 3 essentially point away from the earth's surface. However, it must be noted that such embodiments are also possible with
    which the recordings 3 have different orientations.
    The gripping arm 100 can move goods 2 between the receptacles 3 with one another or move them between the receptacles 3 and an input-output surface 101. This allows simple storage goods 2 to be arranged on the input / output surface 101 so that the gripping arm 100 can stow them in the receptacles 3. If a storage item 2 is required, a command can be sent to the gripping arm 100 via an input unit such as a computer interface in order to initiate the removal. Means such as barcode readers, RFID systems or the like can be provided, which recognize the stored goods and automatically into one
    Classify storage system.
    In an alternative embodiment, each receiving unit 10 can have its own heat sink 202 or, if appropriate, a heat source. The recording units 10 no longer have to have a common one
    Supply line 201 or return line 204 may be connected.
    Within each recording unit 10, the recordings 3 are arranged in rows 12. Each receptacle unit has two line strands 7, which cool the receptacles 3 and are arranged on one side of the receptacles 3 of the receptacle rows 12. In this case, the line strands 7 are connected to one another in series, the transition lines 15 between the line strands 7 being insulated in order to avoid thermal losses. This results in a single temperature control medium path within the receiving unit 10. Alternatively, the receiving rows 12 can also be arranged parallel to one another.
    Fig. 1b shows an alternative, second embodiment, which is very similar to the first. Only the essential differences are dealt with here. A heat sink 202 is assigned to each receiving unit 10. This results in three completely independent, easily transportable functional units 206 which can be operated and moved independently of one another. In the embodiment shown, they are arranged one above the other in the range of motion of the gripping arm 100, so that the gripping arm 100 can load them. In this case, “above one another” means with reference to the ground. Alternatively, each functional unit 206 can also be carried out manually without a gripping arm 100
    Assembly can be used.
    2 shows part of a receiving unit 10, two receiving rows 12 with receptacles 3 arranged in rows being partially shown. Two different rows of receptacles 10 are shown for a better view.
    All the receptacles 3 have a cylindrically shaped receiving opening 4.
    Each receptacle 3 of a first receptacle row 12 has two elastic tempering agent lines 5, these having a circular cross-section in the area of the receptacle opening 4. The one tempering line 5 forms one half and a first part of the jacket of the cylindrically shaped receiving opening 4 and the other forms the other half and thus a second part of the jacket. Together they form a bag that
    Introducing a stored item 2 into a hole 6 of the receiving opening 4 so far expanded
    that the stored goods 2 fit well and at the same time are held against gravity. The tempering agent lines 5 are connected to the tempering agent lines 5 of the adjacent receptacles 3, so that tempering agents can flow through the tempering agent lines 5 of the adjacent receptacles 3 after flowing through the tempering agent lines 5 of a receptacle 3. This results in two continuous cable strands 7, which connect the receptacles 3 to one another. The temperature control lines 5 are connected to one another at one end and are thus flowed through in different directions, as shown by arrows 205.
    The receptacles 3 of the second receptacle row 12 each have only one temperature control line 5, which also have a circular cross-section, covering more than half of the jacket. They are also connected to temperature control lines 5 of the adjacent receptacles 3. This results in a Q-shape of the temperature control lines 5, which form pockets for the stored goods 2. The temperature control lines 5 of the adjoining receptacles 3 are arranged on different sides of the jackets. This results in an alternating alignment of the pockets along the row of receptacles 3.
    The essentially straight connection areas 16 of the line strands 7
    between the receptacles 3 are preferably thermally insulated.
    The temperature control lines 5 are so elastic at least in the area of the receiving openings 4 that no further spring element is necessary. 4a and 4b an alternative embodiment is shown in the additional
    Spring elements are provided.
    FIG. 3 shows part of a wiring harness 7 of the one receiving row 12 from FIG. 2. It can be seen here that the wiring harness 7 is designed as a one-piece flat hose comprising all the temperature control agent wires 5 of this harness. This results in a plurality of curved tempering agent lines 5 which have flat areas which offer a large connection area with the stored goods 2. A main flow 6 flows from an inlet 8 along the
    Shell surfaces of the receiving openings 4 to an exit.
    The temperature control lines 5 are thus flowed through in such a way that the goods 2 are flowed around tangentially about their main axis. This main axis thus extends essentially along the direction of insertion into the receptacle 3. This not only enables uniform cooling of the stored goods 2, but also a simple serial cooling arrangement of a plurality of receptacles next to one another. Alternatively, the temperature control lines 5 can also
    are flowed through axially, for example.
    4a and 4b each show the same receptacle 3 with different storage goods 2 arranged therein. Spring elements 14 are provided at three different heights of the receptacle opening 4 between a fastening wall 9 and the two temperature control lines arranged at the same height and are designed as steel springs. You press the temperature control lines 5 into the receiving opening 4, whereby this is narrowed. The receiving opening 4 has a height H which is delimited on one side by the hole 31 and on the other side by a boundary wall 32. The temperature control lines 5 extend over the entire height H. In an alternative embodiment, the boundary wall 32 can also be arranged at a distance from the temperature control lines 5, as a result of which longer storage goods 2 can also be stored. The spring elements 14 should be so rigid that they also fix stored goods 2 that do not reach the boundary wall 32.
    If, as shown in FIG. 4a, a storage item 2 of small diameter is inserted, the walls of the storage item 2 press the temperature control lines 5 outwards. The elastic spring element 14 give way and enable penetration, the temperature control lines 5 abutting the stored goods 2 and the latter being fixed in the position to such an extent that it cannot leave this position and fall through without external force.
    If, as shown in FIG. 4b, a thicker storage item 2 is introduced, the spring elements 14 bend correspondingly more elastically, as a result of which this too
    can be included and determined.
    The spring elements are evenly distributed in the cross-section of the receiving opening 4 and are of the same elastic design, so that stored goods 2 are always stored
    centered in the receiving opening 4, regardless of its size. In order to
    the stored goods 2 are fixed in a defined position. This is particularly so
    advantageous for outsourcing by a gripper arm 100.
    权利要求:
    Claims (1)
    [1]
    PATENT CLAIMS
    Device (1) for the temperature-controlled storage of stored goods (2), in particular of liquid substances such as blood samples, the device having receptacles (3) for the stored goods (2) and at least some of the receptacles (3) having temperature control lines (5), flows through the temperature control means for temperature control of the stored goods (2), characterized in that at least some of the receptacles (3) having temperature control lines (5) have at least one elastic element for
    Determine the stored goods (2).
    Device (1) according to claim 1, characterized in that at least one spring element (14) as the elastic element, the temperature control line (5) in the direction of a receiving opening (4)
    Presses the receptacle (3) to hold the stored goods (2).
    Device (1) according to claim 1 or 2, characterized in that at least one temperature control line (5) is at least partially elastic.
    Device (1) according to claim 3, characterized in that the temperature control line (5) has at least one layer which is elastic
    is executed.
    Device (1) according to one of claims 1 to 4, characterized in that the temperature control line (5) is designed to at least partially on a storage item (2) arranged in the receptacle (3)
    to lie on.
    Device (1) according to one of claims 1 to 5, characterized in that the receptacle (3) has a receiving opening (4) for receiving the stored goods (2) and that the temperature control line (5) into the receiving opening (4) in an unused position without in it
    arranged goods (2) protrudes into the receiving opening (4).
    Device (1) according to one of claims 1 to 6, characterized in that the temperature control line (5) at least in the area
    11.
    12.
    13.
    14.
    14
    a receptacle 6 opening (4) for receiving the stored goods (2) of the receptacle
    (3) is flat.
    Device (1) according to claim 7, characterized in that a main flow (6) of the temperature control means of the temperature control line (5) leads along the flat area.
    Device (1) according to one of claims 1 to 8, characterized in that the temperature control line (5) extends in the area of the receiving opening (4) substantially over the entire height (H) of the receiving opening (4).
    Device (1) according to one of claims 1 to 9, characterized in that the receiving opening (4) is essentially cylindrical and at least one temperature control line (5) at least one
    Form the first part of the jacket of the receiving opening (4).
    Device (1) according to claim 10, characterized in that the receiving opening (4) is substantially cylindrical and a first temperature control line (5) at least a first part of the jacket and a second temperature control line (5) a second part of the Form the 6S opening.
    Device (1) according to claim 11, characterized in that the first temperature control line (5) and the second temperature control line (5) are arranged substantially at the same height.
    Apparatus (1) according to claim 11 or 12, characterized in that the first temperature control line (5) and the second temperature control line (5) flow in opposite directions (205) of temperature control
    will.
    Device (1) according to one of claims 1 to 13, characterized in that the elastic element has a storage position in the
    Recording (3) arranged goods (2) defined.
    15. The device (1) according to any one of claims 1 to 14, characterized in that the device (1) has at least one receiving unit (10) with a plurality of receptacles (3) and the temperature control lines (5) of the receptacles (3) of the receiving unit ( 10) at least partially
    are connected to each other in series.
    16. The device (1) according to claim 15, characterized in that a plurality of receiving units (10) are provided, the temperature control lines (5)
    are connected together in parallel.
    17. The device (1) according to any one of claims 1 to 16, characterized in that the device (1) has at least one gripping arm (100) for storing, retrieving or relocating the stored goods (2) into or out of the receptacles (2) .
    18. The device (1) according to one of claims 1 to 17, characterized in that at least some of the temperature control lines (5) are connected to at least one heat sink or heat source, which
    preferably has at least one compressor.
    19. The device (1) according to claim 18, characterized in that each heat sink or heat source is assigned a receiving unit (10).
    11/13/2018 MT
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    同族专利:
    公开号 | 公开日
    EP3880153A1|2021-09-22|
    WO2020097653A1|2020-05-22|
    US20210393482A1|2021-12-23|
    AT521831B1|2021-02-15|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US20100084405A1|2008-10-08|2010-04-08|Zeta Holding Gmbh|Device for accommodating receptacles and associated container|
    US20150027434A1|2012-02-21|2015-01-29|Anthrogenesis Corporation|Devices and methods for thawing biological material|CN112066615A|2020-07-28|2020-12-11|西安交通大学医学院第一附属医院|Portable box for blood sampling in clinical laboratory|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    ATA50990/2018A|AT521831B1|2018-11-13|2018-11-13|Device for temperature-controlled storage of stored goods|ATA50990/2018A| AT521831B1|2018-11-13|2018-11-13|Device for temperature-controlled storage of stored goods|
    EP19805117.9A| EP3880153A1|2018-11-13|2019-11-12|Device for storing goods to be stored in a temperature-controlled manner|
    PCT/AT2019/060382| WO2020097653A1|2018-11-13|2019-11-12|Device for storing goods to be stored in a temperature-controlled manner|
    US17/293,034| US20210393482A1|2018-11-13|2019-11-12|Device for storing goods to be stored in a temperature-controlled manner|
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